B0806
Sigma
Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
| Synonym: | Anti-β-Site APP Cleaving Enzyme |
| MDL number: | MFCD03454775 |
Description
| Immunogen | synthetic peptide corresponding to the C-terminus of human BACE-1 (amino acids 485-501). |
| Physical form | Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide. |
Properties
| antibody form | affinity isolated antibody |
| clone | (polyclonal) |
| form | buffered aqueous solution |
| mol wt | antigen mol wt 70 kDa |
| species reactivity | human |
| application(s) | immunoblotting: 1:1,000 using a whole cell extract from the human kidney HEK293 cell line stably transfected with human BACE-1 |
| microarray: suitable | |
| Gene Information | human ... BACE1(23621) |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | NWG |
Related Products
| Array | XP725, Panorama® Antibody Microarray - XPRESS Profiler725 Kit |
References
| reference | Bergmann, C., et al., Independent inhibition of Alzheimer disease β- and γ-secretase cleavage by lowered cholesterol levels. J. Biol. Chem. 283, 11302-11311, (2008) Abstract |
